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Some studies have shown significantly lower activity of SOD in patients with generalised and localised vitiligo [15, 87, 113]

The inclusion criteria were (1) research/review articles on sources and generation of reactive free radicals, (2) research/review articles with experimental data on ROS-associated diseases, (3) research/review articles with experimental data on antioxidant activity, (4) research/review articles exploring the mode of action of synthetic as well as natural antioxidants

The pharmacokinetic profile difference is what matters clinically

I have had my clients say they have had luck with curcumin given by mouth